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HIF1? is present in hypoxia in both phosphorylated andunphosphorylated forms. Transducer pathway Receptor subtypes may bedistinguished by the mechanism through which theiractivation is linked to the response, e.g. Small studies, with large standard errors, could be more likely tohave large effects

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A 3D-pharmacophoremodel was derived from the X-ray crystal structure of the p53 peptide associatedwith MDM2, with several known small-molecule inhibitors.

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